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MARIETTA, Ga., Oct. 30, 2014 /PRNewswire/ –MiMedx Group, Inc. (NASDAQ: MDXG), the leading regenerative medicine company utilizing human amniotic tissue and patent-protected processes to develop and market …

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MiMedx Achieves Record Revenue And Records First Operating Profit

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Newswise WASHINGTON, D.C., October 30, 2014 Researchers at the University of Washington have developed a way to use sound to create cellular scaffolding for tissue engineering, a unique approach that could help overcome one of regenerative medicines significant obstacles. The researchers will present their technique at the 168th meeting of the Acoustical Society of America (ASA), held October 27-31, 2014, at the Indianapolis Marriott Downtown Hotel.

The development of the new technique started with somewhat of a serendipitous discovery. The University of Washington team had been studying boiling histotripsy – a technique that uses millisecond-long bursts of high-intensity ultrasound waves to break apart tissue – as a method to eliminate cancerous tumors by liquefying them with ultrasound waves. After the sound waves destroy the tumors, the body should eliminate them as cellular waste. When the researchers examined these decellularized tissues, however, they were surprised by what the boiling left intact.

In some of our experiments, we discovered that some of the stromal tissue and vasculature was being left behind, said Yak-Nam Wang, a senior engineer at the University of Washingtons Applied Physics Laboratory. So we had the idea about using this to decellularize tissues for tissue engineering and regenerative medicine.

The structure that remains after decellularizing tissues is known as the extracellular matrix, a fibrous network that provides a scaffold for cells to grow upon. Most other methods for decellularizing tissues and organs involve chemical and enzymatic treatments that can cause damage to the tissues and fibers and takes multiple days. Histrostipsy, on the other hand, offers the possibility of fast decellularization of tissue with minimal damage to the matrix.

In tissue engineering, one of the holy grails is to develop biomimetic structures so that you can replace tissues with native tissue, Wang said. Stripping away cells from already developed tissue could provide a good candidate for these structures, since the extracellular matrix already acts as the cellular framework for tissue systems, Wang said.

Due to its bare composition, the matrix also induces only a relatively weak immune response from the host. The matrix could then theoretically be fed with stem cells or cells from the same person to effectively re-grow an organ.

The other thought is that maybe you could just implant the extracellular matrix and then the body itself would self-seed the tissues, if its just a small patch of tissue that youre replacing, Wang said. You wont have any immune issues, and because you have this biomimetic scaffold thats closer to the native tissue, healing would be better, and the body would recognize it as normal tissue.

Wang is currently investigating decellularization of kidney and liver tissue from large animals. Future work involves increasing the size of the decellularized tissues and assessing their in-vivo regenerative efficacy.

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High-Intensity Sound Waves May Aid Regenerative Medicine

JACKSON, Tenn. (PRWEB) October 30, 2014

Dr. Roy Schmidt and the staff of the Pain Specialist Center will host a free seminar and question-and-answer session about regenerative medicine on Tuesday, Nov. 11 at 6 p.m. Held at the clinic at 15 Stonebridge Blvd. in Jackson, the hour-long event will allow attendees to ask questions about stem cell therapy and platelet rich plasma therapy in a relaxed atmosphere. Guests also will have the chance to talk to individuals who have received regenerative medicine treatments, which focus on helping patients relieve pain by supporting the healing process.

Stem cell therapy focuses on delivering the patients own stem cells to parts of the body that are in need. After adipose tissue (comprised of fat cells) is taken from the patients body, it is made into a stem cell concentrate. That concentrate is injected at the focal point of pain or area that needs healing. Schmidt, who is certified to administer stem cell therapy, was trained by Bioheart Chief Scientific Officer Kristin Comella. Comella has been recognized as a national leader in stem cell therapy.

Platelet rich plasma (PRP) or platelet concentrates have been studied extensively since the 1990s. While similar products previously used in medicine (fibrin glue) were very expensive, PRP provides a cost-effective alternative. Plasma concentrates seek to help the body continue the healing process and strengthen the weakened tissue. It is often used for tendon problems, in addition to issues with ligaments, muscles, meniscus, cartilage, bone, wound and intervertebral discs. The supplemental role of hyperbaric oxygen therapy will be discussed at the event, also.

A board certified anesthesiologist, Schmidt has practiced pain management in the Jackson area for two decades. The Pain Specialist Center provides consultation and pain management services to patients suffering from chronic pain syndromes and terminal cancer pain. Individuals can learn more by going online to http://beyondpills.com, http://nopainmd.com and http://hyperbaricoxygentherapies.com, calling 731-660-2056 or e-mailing info(at)beyondpills(dot)com. Event information is on Facebook at http://www.facebook.com/PainSpecialistCenter.

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Seminar on Regenerative Medicine Open to Public

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Newswise In a study led by Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research member Dr. Julian Martinez-Agosto, UCLA scientists have shown that two genes not previously known to be involved with the immune system play a crucial role in how progenitor stem cells are activated to fight infection. This discovery lays the groundwork for a better understanding of the role progenitor cells can play in immune system response and could lead to the development of more effective therapies for a wide range of diseases.

The two-year study was published online October 30, 2014 ahead of print in the journal Current Biology.

Progenitor cells are the link between stem cells and fully differentiated cells of the blood system, tissues and organs. This maturation process, known as differentiation, is determined in part by the original environment that the progenitor cell came from, called the niche. Many of these progenitors are maintained in a quiescent state or “standby mode” and are ready to differentiate in response to immune challenges (such as stress, infection or disease).

Dr. Gabriel Ferguson, a postdoctoral fellow in the lab of Dr. Martinez-Agosto and first author of the study, built upon the lab’s previous research that utilized the blood system of the fruit fly species Drosophila, showing that a specific set of signals must be received by progenitor cells to activate their differentiation into cells that can work to fight infection after injury. Dr. Ferguson focused on two genes previously identified in stem cells but not in the blood system, named Yorkie and Scalloped, and discovered that they are required in a newly characterized cell type called a lineage specifying cell. These cells then essentially work as a switch, sending the required signal to progenitor cells.

The researchers further discovered that when the progenitor cells did not receive the required signal, the fly would not make the mature cells required to fight infection. This indicates that the ability of the blood system to fight outside infection and other pathogens is directly related to the signals sent by this new cell type.

“The beauty of this study is that we now have a system in which we can investigate how a signaling cell uses these two genes Yorkie and Scalloped, which have never before been shown in blood, to direct specific cells to be made,” said Dr. Martinez-Agosto, associate professor of human genetics. “It can help us to eventually answer the question of how our body knows how to make specific cell types that can fight infection.”

Drs. Martinez-Agosto and Ferguson and colleagues next hope that future studies will examine these genes beyond Drosophila and extend to mammalian models, and that the system will be used by the research community to study the role of the genes Yorkie and Scalloped in different niche environments.

“At a biochemical level, there is a lot of commonality between the molecular machinery in Drosophila and that in mice and humans,” said Dr. Ferguson. “This study can further our shared understanding of how the microenvironment can regulate the differentiation and fate of a progenitor or stem cell.”

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UCLA Gene Discovery Shows How Stem Cells Can Be Activated to Help Immune System Respond to Infection



Dr. Lam Discusses PRP, ACell, and ATP at the Hair Transplant 360 Course
http://www.hairtx.com Dallas hair transplant surgeon, Dr. Sam Lam, discusses Regenerative Medicine, including PRP, ACell, ATP at his 6th Annual Hair Transplant 360 Course at St. Louis University…

By: Samuel Lam

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Dr. Lam Discusses PRP, ACell, and ATP at the Hair Transplant 360 Course – Video

SAN DIEGO, Oct. 29, 2014 /PRNewswire/ — ViaCyte, Inc., a privately-held regenerative medicine company, announced today that the first patient in its Phase 1/2 study was successfully implanted with VC-01, its embryonic stem cell-derived islet replacement product candidate being developed as a treatment for type 1 diabetes. This Phase 1/2 clinical trial, designed to evaluate the VC-01 product …

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ViaCyte's VC-01 Investigational Stem Cell-Derived Islet Replacement Therapy Successfully Implanted into First Patient



NexImmune – Company Presentation
Presented by: Scott Carmer, Chief Business Officer NexImmune is an ImmunoOncology company developing products from its proprietary AIMTM technology platform …

By: Alliance for Regenerative Medicine

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NexImmune – Company Presentation – Video

San Diego, California (PRWEB) October 28, 2014

The top stem cell clinic in San Diego, Telehealth, is now offering regenerative medicine procedures for the knee to help restore cartilage and avoid the need for joint replacement. The procedures are outpatient and performed by Board Certified doctors at Telehealth. Call (888) 828-4575 for more information and scheduling.

Hundreds of thousands of knee replacements are performed every year in the US, with most being extremely successful. However, it is a major surgery and there is a chance of complications such as infection or blood clot. Therefore, it is advisable to consider a stem cell procedure for the arthritic knee in an effort to delay or avoid the procedure.

Telehealth provides the procedures with several options, including platelet rich plasma therapy, bone marrow or fat derived stem cells, along with amniotic derived procedures. All of the procedures are outpatient and low risk.

In most cases, the procedures are covered in whole or partly by insurance. Telehealth will perform an insurance verification prior to one’s procedure. The Board Certified doctors at the stem cell clinic in San Diego treat patients from a broad area in Southern California. There are several locations including La Jolla, Orange and Upland CA.

In addition to stem cell procedures for knee arthritis, TeleHealth also provides regenerative medicine options for tendon and ligament injuries, sports injuries along with hip, shoulder and ankle arthritis.

For those interested in avoiding knee replacement with a procedure that can potentially preserve or repair arthritic cartilage, call Telehealth at (888) 828-4575 and visit http://stemcelltherapyincalifornia.com/ for more information.

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San Diego Stem Cell Clinic, Telehealth, Now Offering Knee Procedures for Cartilage Restoration



AGTC – Company Presentation
Presented by: Daniel Menichella, VP Chief Business Officer AGTC is developing cures for rare lung and eye diseases, offering hope to patients with unmet me…

By: Alliance for Regenerative Medicine

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AGTC – Company Presentation – Video



TC BioPharm – Company Presentation
Presented by: Michael Leek, Ph.D., CEO Commercializing the anti-cancer cytotoxicity exhibited by T cells, TC BioPharm is developing an autologous therapy …

By: Alliance for Regenerative Medicine

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TC BioPharm – Company Presentation – Video



How do we use regenerative medicine in cancer treatment? – Prof. Graziella Pellegrini
At congress BIO 2014 we met Professor Graziella Pellegrini. She talks about application of regenerative medicine in cancer treatment. Its main application is…

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How do we use regenerative medicine in cancer treatment? – Prof. Graziella Pellegrini – Video



Download Principles of Regenerative Medicine Free PDF
Download Principles of Regenerative Medicine Free PDF Here http://bit.ly/1znrbJp.

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Download Principles of Regenerative Medicine Free PDF – Video

OTTAWA, Oct. 27, 2014 /CNW/ – Stem cell and regenerative medicine experts representing Canada and international research groups will come together in Ottawa to share some of the leading advances in research, clinical translation and commercialization within the field. The Meetings, co-hosted by the Stem Cell Network and the Centre for Commercialization of Regenerative Medicine (CCRM), will take …

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Ottawa hosts global leaders in stem cell and regenerative medicine research

MIAMI (PRWEB) October 27, 2014

Global Stem Cells Group has announced the launch of the official Regenestem Network website, dedicated to promoting the worlds largest and most recognizable membership organization of regenerative medicine practitioners. The Regenestem Network was developed to promote the Miami-based companys global expansion program and establish affiliate representatives able to bring stem cell treatments, therapies, training courses and conferences to communities worldwide.

In order to become a part of the Regenestem Network, medical practitioners are required to have more than five years experience in the health care industry that includes experience in regenerative medicine. In return, network physicians are entitled to a myriad of benefits and advantages built into the Regenestem Network membership model, including:

Global Stem Cells Group Founder and CEO Benito Novas says that Regenestem Network members also enjoy royalty-free income by committing to the companys established protocols and proven system for the best patient outcomes. Additional benefits of the Regenestem Network membership model include:

Unlike a typical franchise agreement, if you decide to leave us someday we dont take your company away from you, Novas says. We build high quality partnerships with leading stem cell scientists and physicians around the world by establishing mutually beneficial relationships based on professional respect and collaboration.

For more information on the Regenestem Network, visit the Global Stem Cells Group website, email bnovas(at)stemcellsgroup(dot)com, or call 305-224-1858.

About the Global Stem Cells Group:

Global Stem Cells Group, Inc. is the parent company of six wholly owned operating companies dedicated entirely to stem cell research, training, products and solutions. Founded in 2012, the company combines dedicated researchers, physician and patient educators and solution providers with the shared goal of meeting the growing worldwide need for leading edge stem cell treatments and solutions. With a singular focus on this exciting new area of medical research, Global Stem Cells Group and its subsidiaries are uniquely positioned to become global leaders in cellular medicine.

Global Stem Cells Groups corporate mission is to make the promise of stem cell medicine a reality for patients around the world. With each of GSCGs six operating companies focused on a separate research-based mission, the result is a global network of state-of-the-art stem cell treatments.

To learn more about Global Stem Cells Group, Inc.s companies and for investor information, visit the Global Stem Cells Group website, email bnovas(at)regenestem(dot)com, or call 305-224-1858.

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Global Stem Cells Group Announces Launch of Official Regenestem Network Website



McEwen Centre for Regenerative Medicine
McEwen Centre for Regenerative Medicine The objective of this video was to explain what regenerative medicine is, using the actual scientists to describe the…

By: Medtec Video Productions

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McEwen Centre for Regenerative Medicine – Video



Payer Perspectives on Regenerative Medicine Advanced Therapies
This session will explore payer views of advanced therapies such as cell therapy, gene therapy and tissue engineered products. The panel is comprised of repr…

By: Alliance for Regenerative Medicine

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Payer Perspectives on Regenerative Medicine & Advanced Therapies – Video



Koichi Mikami: Regenerative Medicine and Distributions of Responsibility

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Koichi Mikami: Regenerative Medicine and Distributions of Responsibility – Video

Oct 262014

Tuesday

After Hours Network: Meeting. 6-8 p.m., Ragu & Pesto, 6445 Westheimer. Speaker: Dr. Doris Taylor, director of Regenerative Medicine Research at the Texas Heart Institute. Topic: Regenerative medicine. Cost: $15. Information: http://www.afterhoursnetwork.com/.

Houston Entrepreneurs’ Forum: Monthly breakfast meeting. 7-8:30 a.m., Ousie’s Table, 3939 San Felipe. Speaker: Atul Varadhachary, M.D., Ph.D., managing partner at Fannin Innovation Studio. Cost: $27 for members, $35 for guests. Reservations: Tracy Park at 713-822-7260. Online: http://www.heforum.org.

Thursday

IREM Community Involvment Committee: The committee will volunteer at the annual CPS Halloween Party. 2 p.m., Chimney Rock Center, 6300 Chimney Rock. Information: 713-783-9225.

Salary, Family, Climate: What Keeps Women Out of STEM (Science, Technology, Engineering and Math) Fields?: University of Houston John P. McGovern Lecture. 6:30 p.m., University of Houston, University Center Theater, 4800 Calhoun. Speaker: Jennifer Glass, a sociologist at the University of Texas at Austin. Cost: Free. For directions and parking information, visit http://www.uh.edu/uc/about_us/directions.html.

Saturday

The Realty Investment Club of Houston: Meeting. 8:30 a.m. networking, 9 a.m. meeting, RICH Conference Center, 4220 Lockfield. Speaker: Steve Davis, vice president of Lifestyles Unlimited. Topic: The millionaire mindset. Cost: Free for members and first-time guests. Information: http://www.richclub.org or 713-947-7424.

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Meet the Researcher – Oct. 8, 2014
Researchers in the Center for Regenerative Medicine are studying the use of intraspinal deliver of mesenchymal stem cells (MSCs) to the cerebral spinal fluid of patients with ALS using a dose-escal…

By: Mayo Clinic

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Meet the Researcher – Oct. 8, 2014 – Video



Plenary Session: Gene Therapy Gene-Modified Cell Therapies
This session will bring together several of the leading in-vivo and ex-vivo gene therapy companies in addition to pharma companies making a large bet in gene-modified cell therapy. While the…

By: Alliance for Regenerative Medicine

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Plenary Session: Gene Therapy & Gene-Modified Cell Therapies – Video



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